sou nsg6005 Week 8 Assignment 1 Discussion latest 2017

Week 8 Assignment 2
Quiz

1.Question :

When blood glucose levels are difficult to control in type
II diabetes, some form of insulin may be added to the treatment regimen to
control blood glucose and limit complications risks. Which of the following
statements are accurate based on research?

Premixed insulin analogues are better at
lowering hemoglobin A1c and have less risk for hypoglycemia.

Premixed insulin analogues and the newer
premixed insulins are associated with more weight gain than the oral
antidiabetic agents.

Newer premixed insulins are better at lowering
hemoglobin A1c and postprandial glucose levels than are long-acting insulins.

Patients who are not controlled on oral agents
and have postprandial hyperglycemia can have NPH insulin added at bedtime.

Question 2. Lispro
is an insulin analogue produced by recombinant deoxyribonucleic acid (DNA)
technology. Which of the following statements about this form of insulin is not
true?

The optimal time of preprandial injection is
fifteen minutes.

The duration of action is increased when the
dose is increased.

It is compatible with NPH insulin.

It has no pronounced peak.

Question 3. Unlike
most type II diabetics where obesity is a major issue, older adults with low
body weight have higher risks for morbidity and mortality. The most reliable
indicator of poor nutritional status in older adults is:

Weight loss in previously overweight persons

Involuntary loss of 10% of body weight in less
than six months

Decline in lean body mass over a twelve-month
period

Increase in central versus peripheral body
adiposity

Question 4. Sulfonylureas
may be added to a treatment regimen for type II diabetics when lifestyle
modifications and metformin are insufficient to achieve target glucose levels.
Sulfonylureas have been moved to Step 2 therapy because they:

Increase endogenous insulin secretion.

Have a significant risk for hypoglycemia.

Address the insulin resistance found in type
II diabetics.

Improve insulin binding to receptors.

Question 5. The
drugs recommended by the American Academy of Pediatrics for use in children
with diabetes (depending upon type of diabetes) are:

Metformin and insulin

Sulfonylureas and insulin glargine

Split-mixed dose insulin and GLP-1 agonists

Biguanides and insulin lispro

Question 6. Nonselective
beta blockers and alcohol create serious drug interactions with insulin because
they:

Increase blood glucose levels.

Produce unexplained diaphoresis.

Interfere with the ability of the body to
metabolize glucose.

Mask the signs and symptoms of altered glucose
levels.

Question 7. Diagnostic
criteria for diabetes include:

Fasting blood glucose greater than 140 mg/dl
on two occasions

Postprandial blood glucose greater than 140
mg/dl

Fasting blood glucose 100 to 125 mg/dl on two
occasions

Symptoms of diabetes plus a casual blood
glucose greater than 200 mg/dl

Question 8. Adam
has type I diabetes and plays tennis for his university. He exhibits a
knowledge deficit about his insulin and his diagnosis. He should be taught
that:

He should increase his CHO intake during times
of exercise.

Each brand of insulin is equal in
bioavailability, so buy the least expensive.

Alcohol produces hypoglycemia and can help
control his diabetes when taken in small amounts.

If he does not want to learn to give himself
injections, he may substitute an oral hypoglycemic to control his diabetes.

Question 9. Both
ACE inhibitors and some angiotensin-II receptor blockers have been approved in
treating:

Hypertension in diabetic patients

Diabetic nephropathy

Both A and B

Neither A nor B

Question 10. Before
prescribing metformin, the provider should:

Draw a serum creatinine level to assess renal
function.

Try the patient on insulin.

Prescribe a thyroid preparation if the patient
needs to lose weight.

All of the above options are .

Question 11. DPP-4
inhibitors (gliptins) act on the incretin system to improve glycemic control.
Advantages of these drugs include:

Better reduction in glucose levels than other
classes

Less weight gain than sulfonylureas

Low risk for hypoglycemia

Can be given twice daily

Question 12. Prior
to prescribing metformin, the provider should:

Draw a serum creatinine to assess renal
function.

Try the patient on insulin.

Tell the patient to increase iodine intake.

Have the patient stop taking any sulfonylurea
to avoid dangerous drug interactions.

Question 13. Type
II diabetes is a complex disorder involving:

Absence of insulin production by the beta
cells

A suboptimal response of insulin-sensitive
tissues especially in the liver

Increased levels of glucagon-like peptide in
the post-prandial period

Too much fat uptake in the intestine

Question 14. Type
I diabetes results from autoimmune destruction of the beta cells. Eighty-five
to 90% of type I diabetics have:

Autoantibodies to two tyrosine phosphatases

Mutation of the hepatic transcription factor
on chromosome 12

A defective glucokinase molecule due to a
defective gene on chromosome 7p

Mutation of the insulin promoter factor

Question 15. GLP-1
agonists:

Directly bind to a receptor in the pancreatic
beta cell.

Have been approved for monotherapy.

Speed gastric emptying to decrease appetite.

Can be given orally once daily.

Question 16.

Control targets for patients with diabetes include:

Hemoglobin A1c between 7 and 8

Fasting blood glucose levels between 100 and
120 mg/dl

Blood pressure less than 130/80 mm Hg

LDL lipids less than 130 mg/dl

Question 17. When
the total daily insulin dose is split and given twice daily, which of the
following rules may be followed?

Give two-thirds of the total dose in the
morning and one-third in the evening.

Give 0.3 units/kg of premixed 70/30 insulin,
with one-third in the morning and two-thirds in the evening.

Give 50% of an insulin glargine dose in the
morning and 50% in the evening.

Give long-acting insulin in the morning and
short-acting insulin at bedtime.

Question 18. All
diabetic patients with hyperlipidemia should be treated with:

3-hydroxy-3-methylglutaryl coenzyme A
(HMG-CoA) reductase inhibitors

Fibric acid derivatives

Nicotinic acid

Colestipol

Question 19. Metformin
is a primary choice of drug to treat hyperglycemia in type II diabetes because
it:

Substitutes for insulin usually secreted by
the pancreas

Decreases glycogenolysis by the liver

Increases the release of insulin from beta
cells

Decreases peripheral glucose utilization

Question 20. Question
:

Sitagliptin has been approved for:

Monotherapy in once-daily doses

Combination therapy with metformin

Both A and B

Neither A nor B

Explanation & Answer

Our website has a team of professional writers who can help you write any of your homework. They will write your papers from scratch. We also have a team of editors just to make sure all papers are of HIGH QUALITY & PLAGIARISM FREE. To make an Order you only need to click Order Now and we will direct you to our Order Page at Litessays. Then fill Our Order Form with all your assignment instructions. Select your deadline and pay for your paper. You will get it few hours before your set deadline.